Urgent Meds

Korsuva (Difelikefalin)

  • Medicine Name: Korsuva
  • Generic Name: Difelikefalin
  • Dosage Form & Strength: Injection: 65 mcg /1.3 mL (50 mcg/mL) of difelikefalin
  • Manufactured By: Cara Therapeutics, Inc.

Korsuva is a kappa opioid receptor agonist used for the treatment of moderate-to-severe pruritus (itching) associated with chronic kidney disease (CKD-aP) in adults undergoing hemodialysis (HD). This medicinal product is not for use in individuals undergoing peritoneal dialysis (fluid taken from the abdomen).

Recommended Dosage:  The recommended dosage of Korsuva is 0.5 mcg per kg given by intravenous bolus injection into the venous line of the dialysis circuit post each hemodialysis treatment. In case a regularly scheduled hemodialysis treatment is skipped/missed, resume treatment at the end of the next hemodialysis treatment.

Avoid mixing or diluting korsuva injection 65 mcg/1.3 mL (50 mcg/mL) prior to administration. Use the drug within 60 minutes of syringe preparation.

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