Inqovi (Decitabine and Cedazuridine)

Inqovi is a combination of decitabine, a nucleoside metabolic inhibitor, and cedazuridine, a cytidine deaminase inhibitor, used to treat adult patients with myelodysplastic syndromes (MDS), including previously treated and untreated, de novo and secondary myelodysplastic syndromes with the following French- American-British subtypes and intermediate-1/2, and high-risk International Prognostic Scoring System groups. 

Recommended Dosage: Inqovi tablets contain 35 mg of decitabine and 100 mg of cedazuridine.  The recommended dosage is 1 tablet, taken by mouth, once a daily for the first 5 days of each 28-day cycle. Tablets should be taken on an empty stomach, at least a couple of hours prior to or a couple of hours after a meal. After 5 days of treatment, you do not need to take this medicine for the next 23 days. Take your dose one time daily at approximately the same time each day. In case you miss your dose by more than 12 hours, skip that dose and extend your cycle by 1 day. 

• Do not substitute inqovi 35 mg-100 mg tablets for an intravenous decitabine product within a cycle. Consider administering antiemetics before each dose in order to minimize nausea and vomiting. 
• Obtain complete blood cell counts before the initiation of cedazuridine/decitabine, before each cycle, and as clinically indicated to monitor response and toxicity.
• Inqovi (cedazuridine/decitabine) can cause fetal harm in cases administered to a pregnant woman. Verify the status of pregnancy in females of reproductive potential before initiating the therapy.
• Due to the potential for serious adverse reactions in the breastfed child, women should not breastfeed during treatment with cedazuridine/decitabine and for at least 2 weeks following the last dose.
• On behalf of genotoxicity findings, males with female partners of reproductive potential should use effective contraception while on treatment with inqovi tablet and for 3 months after the final dose. 

Urgent Meds is proficient in sourcing INQOVI(Medicines from around the world and has the capability to supply it. We offer global access to the best available treatment for our customers worldwide.

Urgent Meds is committed to dispensing any valid prescription promptly. All prescriptions are dispensed and verified by registered pharmacists and are dispatched only to the patient’s address from New Delhi, India. Your health and well-being are our top priorities.

What is the Generic Name for the trade name drug Inqovi®?

Decitabine and Cedazuridine is Generic Name for the trade name drug Inqovi®.

What is the Manufacturer Name of Inqovi®?

Inqovi® is manufactured by Astex Pharmaceuticals, Inc.

Is Inqovi® approved by the FDA?

Yes, Inqovi® is approved by the FDA. Date of approval: July 7, 2020.

What is Inqovi®?

Inqovi is an oral combination pill developed of decitabine and cedazuridine. Decitabine has been used to treat MDS for so many years, but was previously only available as an intravenous (IV) infusion. Cedazuridine is an ingredient that allows Inqovi to be used by mouth. In clinical trials, Inqovi was shown to be useful in some patients with MDS or CMML.

What is the dosage and form of Inqovi® supplied?

Inqovi® is supplied as Tablets: 35 mg Decitabine and 100 mg Cedazuridine for oral administration.

How long can you take Inqovi®?

Take one tablet, orally, once daily for the initial 5 days of each 28-day cycle. Take tablets on an empty stomach, at least 2 hours prior to or 2 hours after a meal. After 5 days of therapy, you do not need to take Inqovi tablets for the next 23 days.

What are the most common side effects due to Inqovi®?

Most common side effects due to Inqovi® include: rash, fatigue, hemorrhage, myalgia, constipation, mucositis, arthralgia, dyspnea, diarrhea, nausea, dizziness, febrile neutropenia, headache, cough, edema, decreased appetite, pneumonia, upper respiratory tract infection, and transaminase increased.

What are the storage conditions of Inqovi®?

Store at room temperature between 68°F and 77°F (20°C and 25°C). Do not store tablets outside of the original blister pack (plastic sheet containing pills).

How much does Inqovi® cost in India?

The Inqovi cost in India is quite competitive. To procure this medication authentically, you can call or WhatsApp +1-647-818-4196 or send mail to info@urgentmeds.in.

Is it safe to buy Inqovi® tablets online?

Yes, in order to buy Inqovi (decitabine and cedazuridine) online, always look for an authentic, WHO-GDP and ISO certified pharmaceutical wholesaler/distributor/supplier like Urgent Meds.