Rylaze
- Medicine Name: Rylaze
- Generic Name: Asparaginase Erwinia Chrysanthemi (recombinant)¬-rywn
- Dosage Form & Strength: Injection: 10 mg/0.5 mL Solution in a Single-dose Vial
- Manufactured By: Jazz Pharmaceuticals
Rylaze is an asparagine specific enzyme used as a component of a multi-agent chemotherapeutic regimen to treat acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL) in adult and pediatric patients aged one month or older who are hypersensitive to E. coli-derived asparaginase.
Recommended Dosage: When replacing a long-acting asparaginase product, the recommended dosage is 25 mg/m2 administered intramuscularly every 48 hours.
- Because of the risk of severe allergic reactions (life-threatening anaphylaxis), administer this recombinant injection in a setting with resuscitation equipment and other agents required to treat anaphylaxis. Discontinue therapy in patients with severe hypersensitivity reactions.
- Severe thrombotic events, including sagittal sinus thrombosis and pulmonary embolism, have been observed following therapy with L-asparaginase class products. Rylaze needs to be discontinued for a thrombotic event, and administer apt antithrombotic therapy. Consider resumption of Rylaze treatment only in case the patient had an uncomplicated thrombosis.
- Pancreatitis was reported in patients treated with rylaze injection. Evaluate patients with symptoms compatible with pancreatitis in order to establish a diagnosis. Serum amylase and lipase levels need to be assessed in patients with any signs/symptoms of pancreatitis.
- In patients treated with asparaginase class products, hemorrhage may be associated with increased partial thromboplastin time (PTT), increased prothrombin time (PT), and hypofibrinogenemia. Consider apt replacement therapy in patients with severe or symptomatic coagulopathy.
- Elevated bilirubin or transaminases emerged in patients treated with rylaze 0.5 ml injection. Assess bilirubin and transaminases prior to treatment every 2 to 3 weeks during treatment. In the event of severe liver toxicity, discontinue treatment and provide supportive care.
What documents are required to import RYLAZE to India?
RYLAZE (asparaginase erwinia chrysanthemi) injections can be imported by patients or government hospitals on the name of the patients only.
The following documentation is required to import the product:
- Valid prescription from a qualified doctor.
- Patient’s diagnostic reports.
- Patient’s ID proof (issued by the Government of India).
How does the order get confirmed?
The order will be confirmed only after the receipt of:
- Valid prescription from the doctor.
- Import permit if applicable.
Is RYLAZE available in India?
RYLAZE (asparaginase erwinia chrysanthemi injection) is a prescription drug that legally requires a medical prescription to be dispensed.
Urgent Meds helps import cancer medicines on the named patient supply (NPS). We facilitate the following:
- Availability in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune, etc.)
- Medicine price.
- Finding genuine and reliable sources from Canada, Europe, USA, and Australia.
- Ensuring 100% transparency.
RYLAZE can be made available to patients, doctors, and hospitals in Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, Pune, and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and import permit.
Urgent Meds can facilitate the supply of RYLAZE (prescription medicines) to all locations in the world and in India after fulfilling the legal requirements (if applicable).
Please contact +1-647-818-4196 or write us at info@urgentmeds.in for RYLAZE price in India.
We guarantee quality and delivery anywhere in the world as per the buyer’s requirements.
Urgent Meds is able to source the RYLAZE (Cancer Treatment Medicines) from across the globe and has the ability to supply. Urgent Meds offers its customers worldwide access to the best available treatment.
Urgent Meds is able to dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the patient’s address only from New Delhi, India.
What is the Generic Name for the trade name drug Rylaze®?
Asparaginase Erwinia Chrysanthemi (recombinant)-rywn is the generic name for the trade name drug Rylaze®.
What is the Manufacturer Name of Rylaze®?
Rylaze® is manufactured by Jazz Pharmaceuticals.
Is Rylaze® approved by the FDA?
Yes, Rylaze® is approved by the FDA. Date of approval: June 30, 2021.
What is Rylaze 10 mg Injection?
Rylaze 10 mg injection, formerly known as JZP458, is an asparagine-specific enzyme approved to treat acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL) in certain adult and pediatric patients.
What is the dosage and form of Rylaze® supplied?
Rylaze® is supplied as an injection: 10 mg/0.5 mL solution in a single-dose vial for intramuscular administration.
What are the most common side effects due to Rylaze®?
Most common side effects due to Rylaze® include: drug hypersensitivity, pyrexia, abnormal liver test, nausea, musculoskeletal pain, fatigue, infection, headache, febrile neutropenia, stomatitis, decreased appetite, bleeding, and hyperglycemia.
How much does Rylaze cost in India?
The Rylaze cost in India is very reasonable. In order to procure this ALL and LBL medication authentically, you can call or WhatsApp +1-647-818-4196 or send an email to info@urgentmeds.in.
What are the storage conditions of Rylaze®?
Store Rylaze vials refrigerated at 2-8°C (36-46°F) in the original carton to protect from light. Do not shake or freeze.
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